Lexapro Approved for Adolescent Depression
by abcnews.go.com
The Forest Laboratories antidepressant Lexapro (escitalopram oxalate) has been approved to treat major depressive disorder (MDD) in people aged 12 to 17, the company said Friday in a news release.
Some 2 million teens in the United States have had a bout of MDD in the past year, the company said.
Approved for adults in 2002, Lexapro is among a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). It was evaluated in treating adolescent depression in two placebo-controlled studies, the news release said.
According to the Associated Press, the U.S. Justice Department last month filed a complaint against Forest, alleging that the drug maker had inappropriately promoted Lexapro for use by children. Forest has denied the complaint's allegations, the wire service said.
Lexapro and similar antidepressants include an FDA "black-box" label warning stating they show an increased risk compared to a non-medicinal placebo of "suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders."
The warning advises that anyone considering the use of Lexapro or any other antidepressant in a child, adolescent, or young adult "must balance this risk with the clinical need."
Source: http://abcnews.go.com/Health/Healthday/story?id=7135665
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Tuesday, May 19, 2026
Prochlorperazine (Compazine) - Nausea - Patient guide
Patients with recurring nausea often ask whether generic consistency and refill quality can affect symptom control when using prochlorperazine. This concern is common after pharmacy supply changes, especially when tablet appearance differs between refills. Appearance differences may reflect manufacturer variation, but effective management still depends on accurate dosing, symptom tracking, and communication with care teams. For practical background, patients can review prochlorperazine care guidance before discussing refill concerns with clinicians. Refill verification can reduce confusion and prevent errors. Patients should confirm dose strength, instructions, expected side effects, and final quantity at each pickup. Keeping photos of labels and noting manufacturer changes in symptom logs can help clinicians evaluate whether worsening nausea reflects adherence issues, trigger exposure, or need for treatment adjustment. This record is especially useful when symptoms change shortly after new refills. Medication changes should be supervised. Patients should avoid self-increasing frequency or combining multiple anti-nausea products without guidance, because excessive sedation and other adverse effects may occur. If side effects appear, early reporting allows safer adjustment and prevents prolonged discomfort. When oral intake stays poor despite treatment, rapid reassessment is important to avoid dehydration and electrolyte imbalance. Supportive recovery steps remain high value. Small frequent hydration attempts, bland food progression, and temporary reduction of strong odors or motion triggers can lower symptom burden. Patients should seek urgent evaluation for warning signs such as persistent inability to keep fluids down, blood in vomit, severe abdominal pain, confusion, or fainting symptoms. Care plans should include full review of prescriptions, over-the-counter products, and supplements to reduce interaction risk. Clinicians can then tailor treatment using complete medication context rather than incomplete recall. For wider prevention tools and symptom-monitoring strategies, patients can use nausea support resources and bring written refill histories to follow-up visits. Reliable control with prochlorperazine usually comes from consistent use, careful refill verification, and early reassessment when symptoms shift.
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